TY - JOUR T1 - Comparison of clinical .demographic and laboratory data from lower respiratory tract infection due to respiratory syncytialvirus and human metapneumovirus TT - مقایسه علائم بالینی، یافته‌های آزمایشگاهی و دموگرافیک در کودکان مبتلا به عفونت حاد دستگاه تنفس تحتانی با ویروس سنسیشیال تنفسی و متاپنوموویروس انسانی JF - RJMS JO - RJMS VL - 22 IS - 134 UR - http://rjms.iums.ac.ir/article-1-3926-en.html Y1 - 2015 SP - 84 EP - 90 KW - Metapneumovirus KW - Respiratory syncytial virus KW - Children N2 - Background: There is a large overlap among various etiologic agents of lower respiratory tract infections (LRTI). Human metapneumovirus (hMPV) is a novel agent which could cause a similar clinical picture as RSV which necessitate more evaluation in developing countries Methods: In this cross sectional study, pharyngeal swabs from admitted kids with LRTI under 5 years of age were analyzied by RT-PCR methods with standard methods for both viruses and clinical and laboratory parameters were compared by appropriate statistical methods. Results: 32 cases with mean age of 14.31mo (+/- 14.98) were enrolled including 9 cases of Hmpv and 23 cases with RSV infections.56 % cases were female. There was a significant difference between two group regarding mean age [RSV cases were younger (p=0.026)]. Lymphocyte percentage were also significantly different (p=0.02).Also mean body temperature and frequency of cough were different (P values were 0.02 and 0.015 respectively).All RSV cases survived but 2 out of 9 cases of hMPV died. Conclusion: There are some diffrenet clinical and demographic issues which may help to differentiate these two viruses. More prospective studies will be helpful to clarify other possible differences among these viruses. M3 ER -