RT - Journal Article T1 - Study of relationship between total Magnesium and total bilirubin levels in neonates' sera before and after phototherapy JF - RJMS YR - 2012 JO - RJMS VO - 19 IS - 100 UR - http://rjms.iums.ac.ir/article-1-2243-en.html SP - 54 EP - 61 K1 - Magnesium K1 - Neonatal hyperbillirubinemia K1 - Phototherapy. AB -   Background : Binding indirect bilirubin to neuronal membranes receptors such as N-methyl-D-aspartate (NMDA) causes permanent injuries. Magnesium (Mg) ion is proposed to be one of the most important antagonistic regulators of this receptor. We studied relationship between serum levels of total magnesium and total bilirubin before and after phototherapy in term neonates to find new therapeutic and management techniques and the best time for discharge.   Methods: In this semi-experimental, we evaluated icteric neonates whom admitted to Zahedan Imam Ali hospital from March 2009 to March2010. Neonates with symptoms in favor of sepsis, hemolysis and with administration of magnesium sulfate in their mother were not included in this study. The collected data were analyzed by paired sample t-test, and Analysis of Variance via SPSS software.   Results: 90 patients with icterus were studied. Hyperbillirubinemia frequencies before phototherapy included Mild (14-16mg/dl) 28.8%, Moderate (16-18) 33.3% and, Severe (≥18 ( 37.7% Hyperbillirubinemia. Means of billirubin levels were 18.38mg/dl before and 12.99 mg/dl after phototherapy (p LA eng UL http://rjms.iums.ac.ir/article-1-2243-en.html M3 ER -