Volume 26, Issue 4 (7-2019)                   RJMS 2019, 26(4): 1-8 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

ghiasvand S, babakarami F, alavian F, satari M. Evaluation and comparison of antimicrobial effect of graphene oxide and common antibiotics on standard and hospital Resistant Staphylococcus aureus. RJMS 2019; 26 (4) :1-8
URL: http://rjms.iums.ac.ir/article-1-5415-en.html
malayer university , sghiasvand@malayeru.ac.ir
Abstract:   (8275 Views)
Background: Graphene chips are insoluble forms of graphene. Graphene is highly reactive and has no biocompatibility, but after oxidation, it becomes water-soluble. Graphene oxide (GO) is applied in biomedical, including gene and drug transfer, biomedical imaging, biomedical sensors, and antibiotics. Staphylococcus aureus is a gram-positive bacteria and is the most important species in Staphylococcus genus. Regarding the resistance of bacteria, biocompatible materials as antibiotics are important. The purpose of this study was to evaluate the antimicrobial properties of GO nanoparticles on Staphylococcus aureus.
Methods: GO was produced using Homer method. In this study, after bacterial culture (hospital and standard), antimicrobial effect of GO alone and with conventional antibiotics, halo diameter test, and spectroscopy method was measured. MBC and MIC were used to measure the effects of different specimens
Results: The results of this experiments showed that the GO decreased bacterial growth. Also, the results of treatment with GO and antibiotics showed a synergic effect. Statistical analysis of data obtained from synergism of erythromycin and gentamicin antibiotics was significant.
Conclusion: Due to the resistance of bacteria, the production of new antimicrobial agents has always been considered. Since GO improves the inhibitory effect of antibiotics and given that the cost of its production is relatively economical, it seems that graphene oxide can be used as a new drug compounds.
 
Full-Text [PDF 764 kb]   (1223 Downloads)    
Type of Study: Research | Subject: Microbiology

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Razi Journal of Medical Sciences

Designed & Developed by : Yektaweb