ABSTRACT

A 40 year-old man was referred to our center with obstructive uropathy. In spite of removing the stone, serum creatinine remained high, so a kidney biopsy was performed. Acute Tubulointerstitial Nephritis “TIN” was reported by light microscopy, Linear deposition of IgG and C3 along tubules were detected by immunofluorescence studies. In his serum Anti – TBM activities was also detected which was of IgG class. Plasmapheresis and immunosuppressive treatment were very effective in this patient. To the best of our knowledge this is the first confirmed case of Anti – TBM, reported in Iran.