Abstract: (9614 Views)
ABSTRACT
Due to high prevalance of mumps infection in Iran, (in results of no routine vaccination of children with mumps vaccine) and sequale of its that mostly manifestes as meningoencephalitis (M,E) for detection of ferequancy, clinical course and complication of mumps meningo encephalitis in children less than 15 years this longitudinal study was done in mumps meningoencephalitis patients whom admited in pediatric ward of Rasool Akram & Firroz Abadi Hospital in 1995-1997. These patients grouped in Benign and malignant group regard to duration of hospital stay and complication. 70% of all grouped in benign form M.E, that discharged without sequle in 5 th day of admission, Remanant of patients(30%) grouped as malignant M.E, died (1 case) or discharged after 5 days and with sequles (Recurrent convulsion, hydrocephallus, cerebellitis, facial palsy, sensory neural hearing, changes loss…). These two groups compared for age, sex,season, positive CSF findings. Mean age of patients was higher in malignant form than benign form of M.E.Two form of M.E were seen in spring season. Benign form of M.E were higher in spring and summer, but malignant M.E were equal in winter and spring, No cases of malignant form were seen in Autumen. M/F ratio of ME was 4/1, No sex diferrence were seen two groups, positive CSF finding (Aseptic meningitis) was due to benign form. (Pvalue, 0.01) Results compare with studies in developed countries (prevaccination period). It was determined that complication of mumps M.E in this study probably more common than previous studies in developed countries.
Type of Study:
Research |
Subject:
Infectious Disease