We report on the occurrence of a necrobiotic palisading granuloma in the dermis, resulting from intralesional injection of corticosteroid in a 6-year-old boy with previous history of a cutaneous ulcer and formation of hypertrophic scar. Granulomatous inflammation frequently forms around either endogenous or exogenous material that comes in direct contact with the dermis where it is perceived as a foreign. The injection of corticosteroids into the skin results in the appearance of granular material in the dermis or much less commonly a granulomatous reaction resembling rheumatoid nodule.

Keywords: 1) Necrobiotic palisading granuloma 2) Corticosteroid 3) Skin

Full-Text [PDF 480 kb]   (4337 Downloads)