Introduction: Liver neoplasm is not an uncommon disease in Asian countries. Liposarcoma is a rare mesenchymal malignant tumor which usually originates in the retroperitoneum and extremities .From 1973 uptil now about 10 cases of primary liver liposarcoma have been reported.In this article we present the eleventh case in a young adult female.

  Case report: The patient was a 21 year old female who presented with fever, dyspnea and abdominal pain.She suffered from huge mass in the right lobe of liver with constitutional symptoms and respiratory distress. Despite aggressive surgery, the tumor recurred after six months and led to her death after a year.

  Conclusion: Hepatectomy is the best strategy to achieve a long term survival in these patients, as the tumor is highly invasive, has an increased rate of recurrence and the effect of radiotherapy and chemotherapy is unclear.