Volume 15 - Autumn,Winter                   RJMS 2009, 15 - Autumn,Winter: 133-139 | Back to browse issues page

XML Persian Abstract Print

Abstract:   (8735 Views)

    Background and Aim: Inflammation is relatively a documented pathogenic cause of chronic rhinocynositis and nasal polyps, but the definite causes are still unknown. Among the infective causes, we decided to evaluate Mycoplasma and Chlamydia, the two major pathogens in respiratory tract diseases, as a potential etiologies in nasal polys.

Materials and Methods: In a descriptive-analytic cross-sectional study, 51 patients with nasal polyp and 19 healthy persons (with nasal fracture) who had referred to



Hospital were enrolled in the study. Blood sample for ELISA and nasal polyp tissue (in control group a specimen from inferior nasal turbinate mucosa) for PCR tests were sent to the laboratory. Descriptive measures, Chi-square and Mac Nemar tests and Kappa agreement statistics were used for statistical analysis.

Results: Positive results for IgM, IgG and PCR for Chlamydia were 9.8%, 47.1% and 7.8% in patients and 0%, 47.4% and 0% in control group, respectively. The differences between the groups were not statistically significant. Similarly for Mycoplasma, the above mentioned results were 15.7%, 68.6% and 19.6% in patients and 15.8%, 47.4% and 0% in control group, respectively. According to IgG and PCR results, the differences between two groups seems to be significant (P =0.10 and 0.05 respectively).

Conclusion: Between the two evaluated bacteria in this study, mycoplasma may have significant correlation with nasal polyp formation. However further studies with larger sample size and considering more confounding factors are needed.

Full-Text [PDF 218 kb]   (4446 Downloads)    
Type of Study: Research | Subject: ENT

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.