@article{ author = {Javadi, Azadeh sadat and Heydarinasrabadi, Mitra and Bakhshikhaniki, Gholamrez}, title = {Histopathological assesment of sargassum tenerrimum algae extract effect on the mice bone tissue with osteoporosis}, abstract ={Background and purpose: Osteoporosis is a silent disease which is causing death of significant population due to bone fractures. Use of natural supplements is considered with respect to side effects of chemical drugs. In this study, the effect of sargassum algae on osteoporosis disease was investigated. Method: The study was done on 80 mice heads of NMRI race. After osteoporosis induction, the mice divided into the control, sham, positive control, experimental and negative control groups. The therapeutic dose of positive control group was 125 mg/kg/day of calcium and 0.025 μg / week / mice vitamin D and that of in the experimental group was 10mg/100g(bw)/day Sargassum algae extract that was fed for 28 days to each group. Finally, histopathology sections were studied. Findings: The negative control group had more degradation in lamellar bone (bone blades) than other groups (P<0.01). The experimental group had less degradation compared to negative control group and also, the number of observed osteoblasts in the periosteum had a significant increase than negative control group. (P<0.01) Result and discussion: Our study showed that Sargassum tenerrimum algae has meaningful effect on osteoporosis and since includes active ingredients with absorbable calcium; it can have the ability of osteoporosis inhibition from several ways. Also, it was shown that algae has unique effect in ossification process and inhibition of osteoclast production via activation of Smad and BMP path, RANK protein inhibition and TNFα.}, Keywords = {osteoporosis,Mouse,Sargassum algae,Histopathology}, volume = {24}, Number = {155}, pages = {1-10}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4480-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4480-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Ramezankhani, Ali and Pooresmaeili, Ameneh and Rakhshandehrou, Sakineh}, title = {The Effect of group discussion method Educational on Knowledge, Attitude and Preventive Behaviors of high blood pressure in women 20-49 years old Islamshahr Cit}, abstract ={Background: Nowadays, high blood pressure is the most important risk factor for heart disease, stroke and kidney diseases and education is one of the most effective factors that reduces high blood pressure. This study aimed to determine the effect of education on knowledge, attitude and preventive behaviors of high blood pressure based on group discussion in women 20-49 years old Islamshahr City. Methods: This research is an interventional study. Samples were selected by random cluster sampling methods, 112 mothers of elementary school girls and boys were divided in two groups (n=56 per group). Subjects completed the researcher-made questionnaire in the first stage. Then, an educational program covering 2 one-hour sessions of group discussion was held for 4 groups, each having 10 members and 2 groups of 8 members (2 sessions per week). Two months after intervention, the questionnaires were completed by the subjects. Data was analyzed by chi-square test and ANOVA with repeated measure was used with SPSS21. Results: After intervention, knowledge scores increased in the intervention group compared to the control group (p<0.001). Also attitude and behavior after intervention were significantly increased in the intervention group compared to the other one (p<0.001). Conclusion: The results showed that discussion method in the intervention group had a significant effect on knowledge, attitudes and behaviors of high blood pressure.}, Keywords = {Keywords: high blood pressure, Knowledge, Attitude, Behavior, group discussion}, volume = {24}, Number = {155}, pages = {11-19}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4471-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4471-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {amini, Fateme and vaziri, Siavash and Karimpour, Hassan Ali and hassani, shima and Mohamadi, Saeed and azizi, mohse}, title = {The study of frequency and antibiotic resistance pattern of urinary tract infection pathogens in children of Kermanshah in 2015}, abstract ={Abstract Background: Urinary tract infection is the most prevalent childhood infection and because of its complication requires antibiotic therapy. The aim of this study was frequency determination and antibiotic resistance pattern of UTI pathogens of children under 15 years old in Kermanshah. Methods: This cross-sectional study was carried out on 121 positive urine cultures of children in 2015. After microorganism determination, antibiotic susceptibility test was done with disc diffusion method. Results: Of  total 121 sample %69.4 were girls, %30.6 were boys and most of cases were girls under 2 years old. The most prevalent pathogens were E.coli (%71.1), Enterobacter (%14.9) and other pathogens (%14).Without considering the pathogen most antibiotic resistance were seen in ampicillin %90.8  coterimoxazol (%70.2) cephalexin (%67.7) and the most susceptibility were seen in ciprofloxacin (%82.7) and nitrofurantoin(%76.9) respectively. Conclusion: In this study, ciprofloxacin and nitrofurantoin were the most effective antibiotics, which make these antibiotics valuable in UTI treatment. In addition, the increasing rate of cephalosporin resistance could be due to inappropriate consumption of these drugs. As a result, accurate attention to appropriate prescription of antibiotics, identifying the UTI pathogen and periodical epidemiological studies for identifying the resistance pattern seems necessary.}, Keywords = {Keywords:Urinary tract infection, Antibiotic resistsnce, children}, volume = {24}, Number = {155}, pages = {20-27}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4513-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4513-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Ameri, Zahra and Armin, Farzaneh and Farsinezhad, Alirez}, title = {Platelet cold agglutinin-induced pseudo thrombocytopenia in a patient with colorectal cancer presenting for bowel resection}, abstract ={Background: Cold antibody induced platelet clumping is a rare in-vitro phenomenon that causes EDTA independent pseudo thrombocytopenia. This pre-analytical problem leads to a challenge in the clinical laboratory. In such a case platelets tend to easily aggregate in vitro, giving rise to lower platelet counts. The error is detected simply by examining peripheral blood smear. This report describes a 77 year old man with colon cancer who has received 10 units of random donor platelets due to an analytical error. Case report: Blood sample was collected on EDTA and sodium citrate anticoagulants and counted in different times and various temperatures by cell counter to detecting the cause of thrombocytopenia. The patient had no signs of bleeding. Platelet count was 164000/µl immediately after sampling but declined sharply after 5 minutes. Platelet clumps was seen at the end of peripheral blood smear. We conclude that cold agglutination induced pseudothrombocytopeniais rare phenomenon which resulting in misleading laboratory results. Conclusion: This condition should be considered in severe thrombocytopenia without abnormal bleeding manifestation. Since the cold coantibodies did not affect platelet function, this patients will not suffer complications from their platelet cold agglutinin, but it could pose a problem under circumstances such as extensive surgery with associated with hypothermia}, Keywords = {Keywords: platelet agglutination, pseudothrombocytopenia, cold agglutinin, in vitro agglutination}, volume = {24}, Number = {155}, pages = {28-32}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4569-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4569-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Jahangiri, Samira and Onsori, Habib}, title = {Investigation of the GJB2 gene Mutations among Subjects with Non-Syndromic Sensorineural Hearing Loss}, abstract ={Background: Hearing impairment as a heterogeneous disorder is the most common sensory defect that occur 1 in 1000. Mutations in GJB2 (CX26) gene at DFNB1 locus on 13q12 are responsible for autosomal recessive non-syndromic hearing loss (ARNSHL) in many populations. This study investigates the GJB2 gene mutations in deaf patients refereed to the deaf center of Tabriz. Methods: In the present descriptive- laboratory study, 50 patients with NSHL were selected from the deaf center of Tabriz, Iran. After taking 5 ml blood samples (5ml) from the patients, genomic DNA was extracted using the Rapid Genomic DNA Extraction (RGDE) method. In this study, detection of common mutation in GJB2 gene (35delG) using AS-PCR method and other mutations with direct sequencing of amplified fragments of coding region was performed. Results: In this study, only 35delG mutation was observed in the GJB2 gene. From 50 deaf persons, 16 patients (32%) were homozygous, 7 patients (14%) were heterozygous and 27 patients (54%) were normal for 35delG mutation. In heterozygous and normal individuals for 35delG mutation, another mutation was not observed. Therefore, the frequency of 35delG in the study population is 39%. Conclusion: The results of this study show that, 35delG mutation is the most common mutation in the cause of hearing loss in the patients, but other genes are involved in the pathogenesis of deafness and further studies are needed to identify them. Therefore, mutation screening of individuals with hearing loss referred to genetic counseling centers before marriage and pregnancy is recommended.}, Keywords = {: Hearing loss ,GJB2, Mutation}, volume = {24}, Number = {155}, pages = {33-39}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4475-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4475-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Zandi, Babak}, title = {Comparison of Dental Signs of Fluorosis Between Workers of Two Industrial Factories in Markazi Province, Iran}, abstract ={Background: Considering the importance of examining the effects of fluorine and its compounds on aluminum industry workers, this study aimed to compare the signs of dental fluorosis between the workers of one of the aluminum factories and one of the industrial equipment construction companies of Markazi province in Iran. Methods: This descriptive study was performed on 351 workers of one of the aluminum factories of Markazi province (company A) and 220 workers of one of the industrial equipment construction companies of the same province in Iran (company B). The teeth of all the subjects were examined. Workers in company B were considered as the control group. Data were entered into SPSS software 13 and analyzed by using appropriate method analysis. Results: We found a significant relationship between the occurrence of dental fluorosis and age and work experience. The rates of dental fluorosis were 34.47% and 17.27% in the company A and company B, respectively. The findings showed that there was a significant difference between the company A and company B regarding the prevalence of dental fluorosis (p>0.05). The most common dental sign in workers of company A was perikymata, while tooth discoloration was most frequently observed in the company B. Conclusion: Our study revealed that the prevalence of dental fluorosis in aluminum factory was higher than industrial equipment construction company, which exacerbated with increasing age and working history. Oral health training and the use of safety equipment in the workplace are of great significance for workers exposed to fluorine and its compounds.  }, Keywords = {Dental fluorosis, Fluorine, DMFT index, Aluminum}, volume = {24}, Number = {155}, pages = {40-49}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4543-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4543-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Mohammadi, Mohsen and Mohammadpour-Mir, Ali and Dehestani, Anahid and Mohammadzadeh, Iraj}, title = {The survey of prevalence of Allergic Disorders in chronic sinusitis of children referred to infectious, immunologic and allergic diseases’ clinic of Amirkola children’s hospital in 1390-91}, abstract ={Background: Chronic sinusitis is one of the most common diseases in childhood that can lead to a lot of complications. Many risk factors are considered to be responsible for the disease. An allergic disorder seems to be one of the most important risk factors. The role of allergic disorders in chronic sinusitis is currently unclear. Also no comprehensive study has been done yet in our country. Therefore in this study the prevalence of allergic disorders in children with chronic sinusitis had been evaluated. Methods: This cross-sectional study was done in children between 3-14 years old (mean age 6.98 +/- 2.9) with signs and symptoms of chronic sinusitis, who had referred to infectious & immunologic clinics of pediatric Hospital of Amir Kola in years of 2011-2012. 120 individuals were considered for our study, the sampling was done randomly. Population was divided by age into three groups (1-4 years, 5-9and, 10-14 years old). The data were collected by Questionnaire and check list and analyzed by SPSS 20 software and the appropriate statistical tests (T-test, Chi square). Results: The prevalence of children with chronic sinusitis were identified in each age group as following: (1-4) 31 (25.8%), (5-9) 67 (55.8%) and (10-14) was 22 (18.3%). There were 79 males (65.8%) and 41 females (34.2%) in the total population. Seasonal distribution was evaluated in this study as following: spring 31 (25.8%), summer 16 (13.3%), fall 37 (30.8%) and winter 36 (30%). Prevalence of allergic rhinitis in the general population was 30.0%, Asthma’s prevalence was 17.5% and the prevalence of atopic dermatitis was 0% in our study. The overall prevalence of allergic disorders was 36.66%, among which 10.83% of the total population had both asthma and allergic rhinitis and 25.83% had just one of them. There was no significant association between asthma and the age, sex or season (p<0.05). Relationship between allergic rhinitis and the mentioned factors was irrelevant as well. Conclusion: Our study showed that the prevalence of chronic sinusitis in the (5-9 years) age group, males and the fall season is more. Allergic rhinitis had the most prevalence among allergic disorders; asthma was the second most common. It seems diagnosis and treatment of these diseases can be helpful in prevention and the development of chronic sinusitis.}, Keywords = {Chronic sinusitis, Allergic rhinitis, Asthma, Atopic dermatitis, Prevalence, Pediatrics}, volume = {24}, Number = {155}, pages = {50-56}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4528-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4528-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Shakiba, Shila and Shojaeizadeh, Davood and Sadeghi, Roya and Azam, Kamal and Kia, Fatemeh}, title = {The impact of nutritional education on improving the nutritional behavior reduces the severity of menstrual pain therapy personnel in Imam Khomeini hospital}, abstract ={Background: Dysmenorrhea implies to the unusual feeling of pain in the lower abdomen during menstruation which can cause the person to stop her daily activities. This study aimed to determine the impact of nutritional style modification on reducing the severity of menstrual pain in female health personnel of Imam Khomeini hospital. Methods: In this interventional study, after interviewing 120 employed people, 50 individuals with an average age of 31.48±5.08 (22-45 years) entered the study. Test information was gathered through a questionnaire, multidimensional scale to determine the degree of menstrual pain, visual form and registration checklist that registered pain severity of dysmenorrheal. The nutritional education program, along with visual form was given to the participants to complete each month and the registration checklist of dysmenorrhea to complete at the end of the intervention.After 3 months, data was collected and analyzed using spss software version 19, descriptive test, paired T-test and anova repeated measure test. P<0.05 was considered as significant level. Results: Nutritional education intervention, made a significant reduction in the average severity of menstrual pain in participants (p<0.001). Complications of dysmenorrhea after the intervention showed a significant reduction (p<0.001). Conclusion: Nutritional education intervention makes the promotion of nutritional behaviors and reduces dysmenorrhea in women. Therefore, with regard to its cost-effectiveness and efficiency, you can use it to reduce dysmenorrhea.}, Keywords = {Educational intervention, Dysmenorrhea ,The severity of pain}, volume = {24}, Number = {155}, pages = {57-65}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4108-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4108-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {Mansoori, Majid and Janani, Somayeh and Chavoshi, Delina and Mohaghegh, Pegah and Hemmatpouقr, Siroos and Fatolahpour, Asadolah and Moradi, Ghob}, title = {Evaluation of the Side Effects and mortality of Surfactant therapy with mechanical ventilation comprise with manual ventilation in Neonates Admitted to NICU ward of Besat hospital of Sannandaj in 2012-2013}, abstract ={Background: Respiratory distress syndrome is one of the main causes of infant mortality. Surfactant is the standard treatment for it. In this study, complication of surfactant therapy via mechanical ventilation and manual injection were compared in neonates with respiratory distress syndrome admitted in neonatal intensive care unit of Besat hospital in Sanandaj. Methods: In this retrospective cohort study, 160 infants with respiratory distress syndrome were studied. The patients included 75 patients (46.8%) in whom surfactant was administered by injection via manual ventilation and 85 patients (53.2%) in whom it was administered by mechanical ventilation. Data were entered into the software STATA-11 and t-test and chi-square was used. Results: Of the 160 preterm neonates, 116 (69%) cases were female and 52 (31%) cases were male. The mean duration of mechanical ventilation (p=0.024) and the mean duration of oxygen therapy (p=0.018) in two groups were statistically significant. Pneumothorax rate, prevalence of Bronchopulmonar Dysplasia (BPD) and mortality rate were different between two groups but weren't statistically significant. Conclusion: The results showed that the duration of mechanical ventilation is less in surfactant therapy with mechanical ventilation compared to manual ventilation. Considering the fewer complication of surfactant therapy with mechanical ventilation, it is recommended as a better method for surfactant administration than manual ventilation.}, Keywords = {Preterm infant, Respiratory Distress Syndrome, Surfactant therapy, mechanical ventilation}, volume = {24}, Number = {155}, pages = {66-72}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4054-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4054-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} } @article{ author = {tavakolizadeh, jahanshir and Rahmani, Motahhare and safarzade, somayeh}, title = {Emotional intelligence of students: Examining Predictive Role of assertiveness and aggression of parent}, abstract ={Background: Emotional intelligence as a basic psychological constructs to the success of life and mental health of people formed in the process of life and behavior of parents plays an important role in its growth. This study aimed determines the predictive role of assertiveness and aggression in emotional intelligence of students of sixth grade of elementary school. Methods: The present study was Cross-sectional. The study population of present study consisted of all students of the sixth grade of elementary school of Qaen city and parents in academic year of 2013-2014 that 189 students (94 boys and 95 girls) and their parents using multi-stage random sampling method were selected from among them. Data were collected using The Aggression Questionnaire- AQ, Gambryl and Ritchie assertiveness questionnaire and The Schutte Self Report Emotional Intelligence Test (SSEIT). The results were analyzed using SPSS-20 software and regression, independent t test and Mann-Whitney U test in the significant level of 0.05. Results: The results showed that between assertiveness of parents and none of its components and emotional intelligence of students there is no significant correlation (p>0.05). But There was significant negative correlation between aggression of parent and emotional intelligence of students (p>0.01, r=-0.18). Regression analysis showed aggression of father is a predictor of emotional intelligence of students (p>0.05). But, aggression of mother had no role in predicting emotional intelligence of students (p>0.05). Conclusion: The results of present study showed that aggression of parents causes that children face in the process of emotional intelligence with problems and limitations. Given that, the behavior of parents affect on the behavior and how to train of children in the family. So, it is recommended more attention in the parenting of children and parental lifestyle.}, Keywords = {Aggression, Assertiveness, Emotional intelligence, Parent, Students}, volume = {24}, Number = {155}, pages = {73-82}, publisher = {Iran University of Medical Sciences}, url = {http://rjms.iums.ac.ir/article-1-4280-en.html}, eprint = {http://rjms.iums.ac.ir/article-1-4280-en.pdf}, journal = {Razi Journal of Medical Sciences}, issn = {2228-7043}, eissn = {2228-7051}, year = {2017} }