per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-09
18
87
1
7
article
Evaluation of associated anomalies with imperforated anus in 10 years study (1999-2008) in children hospitalized at Ali-Asghar Hospital
Salaheddin Delshad
1
Mohammad Kazem Oladghobad
2
Laily Najafi
3
Background: Imperforate anus is a common anomaly associated with many other anomalies. The aim of this study is determining the frequency of associated anomalies in children with imperforated anus. Methods: This retrospective, cross sectional study was conducted by 245 neonates and children (137 male, 105 female and 3 ambiguous genitalia) with imperforated anus diagnosis, in Ali-Asghar hospital 1999 – 2008. Our information was extracted from patient’s files and charts. SPSS 17 used for data analysis. Results: 50.6% of the patients had associated anomalies which included 18% cardiovascular, 15.5% renal, 14.7% gastrointestinal, 13.9% vertebral, 13.1% genitourinary, 8.2% external genitalia. The most prevalent associated anomaly in this study was genitourinary system anomalies and also cardiovascular anomalies in the second rank. Conclusion: Patients with imperforated anus should undergo a detailed general physical, systemic and radiological examination (Infant gram, Echo cardiography, Ultrasonography of urogenital system) in neonatal period to detect associated anomalies in early period.
http://rjms.iums.ac.ir/article-1-1827-en.pdf
Imperforated Anus
Associated Anomalies
Frequency
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-09
18
87
8
13
article
Evaluation of pentoxifylline effect in treatment of Ankylosis Spondylitis patients referred to Hazrat Rasool Akram Hospital
Fatemeh Shirani
1
Seyed Mehdi Sebt Rozati
2
Background: Ankylosing spondylitis (AS) is a spondyloarthropathy of unknown etiology, with widespread effect on axial and peripheral skeleton. The aim of this study was determination of Pentoxifylline effect on BASDAI number of uncontrolled AS patients in Rasool-e-Akram hospital rheumatology clinic. Methods: This pilot study was performed on 30 patients with ankylosis spondylitis with BASDAI ≥ 4 without attention to previous medical treatment. Pentoxifylline tablets administered 400 mg TDS and patients evaluated at 6 and 12 weeks after treatment. Data were analyzed by Paired T test and p<0.05 was significant. Results: 30 patients (26 = Male (86.7%), 4 = Female (13.3%)) with Ankylosing spondylitis was evaluated. Mean age of patients was 32.42±8.14. mean ± standard deviation of BASDAInumber in our patients was 6.53±1.72 at baseline, which decreased to 5.17±1.58 at 6 weeks and 4.88±1.66 at 12 weeks of treatment.(P=0/000) Between BASDAI before and after treatment with Pentoxifylline differences was significant. Conclusion: Pentoxifylline can be advised for uncontrolled AS patients regardless of current or previous treatment.
http://rjms.iums.ac.ir/article-1-1828-en.pdf
Analyzing spondylitis-BASDAI (Bath Ankylosing spondylitis Disease activity index)-Pentoxifylline.
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-09
18
87
14
23
article
Evaluation of serological diagnosis indirect Immunofluorescence and ELISA in comparison to direct examination and culture in vulvovaginal candidiasis
Mina Sharifi Sorkherizi
1
Mehraban Falahati
2
Farideh Zeini
3
Lame Akhlaghi
4
Fariba Haydari-Kohan
5
Mohsen Ghelman
6
Somayeh Sharifiniya
7
Background : Vulvovaginal candidiasis occurs due to the overgrowth of candida in genital system mucosa of females. Symptoms and signs of vulvovaginal candidiasis are unspecific, therefore its diagnosis based on them (symptoms and signs) is not certain. The aim of this research was comparison the result of indirect immunofluorescence and ELISA with culture and direct microscopy examination in patient with vulvovaginal candidiasis. Methods : This was acomparative-descriptive study that was performed on 87 patients and 50 normal cases. All specimens were examined under direct microscopy, culturing and complimentary test to differentiate the candida species from each other. Serological tests such as indirect immunofluorescence and ELISA were performed on sera of the patients. To compare the quantitative and qualitative data in order t-student test, chi-square and exact fisher test were used, if necessary. Results : Out of 87 specimens ,50 cases were diagnosed as vulvovaginal candidiasis. In order , frequency of the isolated pathogens were: C.albicans, C.glabrata,C.kefyr , C.inconspicua and C.famata. Also in order frequency of control groups were: C.albicans, C.glabrata and C.kefyr. In this study all of normal cases were negative in indirect immunofluorescence test and in patients group 42 person(84%) were positive and 8 (16%) negative. Control groups were negative in ELISA and in patient group 40 person(80%) were positive and 10 person(20%) negative. Conclusion : It seems in cases that are not possible to perform direct microscopic and culturing methods, ELISA and indirect immunofluorescence can be used as a replacement method.
http://rjms.iums.ac.ir/article-1-1829-en.pdf
Vulvovaginal candidiasis
diagnosis tests
indirect immunofluorescence ELISA .
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-09
18
87
24
35
article
Occupational stress and influencing factors, in medical residents of one of the educational hospitals of Tehran University of Medical Sciences
Maryam Malek
1
Saber Mohammadi
2
MirSaeed Attarchi
3
Background: Occupational stress is one of the most common hazards in workplaces and leads to different physical, mental, and behavioral outcomes and complications. Medical residents, due to the nature and characteristics of their job, confront various stressors. This study has been designed in order to identify the frequency of occupational stress in medical residents and factors influencing it. Methods: This cross-sectional study was conducted on 305 residents in various specialties in Rasoul-e-Akram Hospital on spring 1389. For measuring the degree of stress, we used Osipow occupational stress inventory. T-test, Chi-Square, ANOVA and Logistic regression were used to evaluate associations. Results: Response rate was 87%. Most of the residents had moderate stress. Average score of total stress was 147.06 from 250. The most frequent stressor was work overload (31.05 from 50) and responsibility (29.55 from 50). Stress significantly increased with shift work (OR=4.591, CI=1.31-16.13, P=0.017), surgery (OR=3.769, CI=2.10-6.76, P=0.001) and also correlated with lower rest time (OR=1.962, CI=1.12-4.08, P=0.048) and higher weekly work hours (OR=1.242, CI=1.10-2.34, P=0.050). Conclusion: As mentioned the most frequent stressors were work over load and responsibility, so it is recommended that in order to reduce stress, work hours must be limited and support residents more properly. In addition, some education and consultation for specialty choice must be giving to the physicians.
http://rjms.iums.ac.ir/article-1-1830-en.pdf
Job stress
medical residency
Stressor
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-09
18
87
36
43
article
Evaluation of relation between the retinal nerve fiber layer and Expanded Disability Status Scale (EDSS) in patients with relapsing-remitting form of multiple sclerosis referring to Rasool Akram Hospital
Mehdi Moghaddasi
1
Atefeh Hosseini Nasab
2
AmirAli Shirali
3
Mostafa Soltan Sanjari
4
Background : Early diagnosis of multiple sclerosis disability is very important in managing patients. The aim of this study is to use Heidelberg Retinal Tomography (HRT) to evaluate the Retinal Nerve Fiber Layer (RNFL) of MS patient as a predictor factor of their disability scales. Methods : In this cross-sectional study a total of 69 patients with RR.MS were included on the revised McDonald criteria. They were examined by a neurologist to calculate their EDSS scores. Demographic information and related data of patients such as history of Optic Neuritis (ON) and using Interferones were taken. Patients were referred to ophthalmology department of Rasool Akram hospital to assess their RNFL thickness using HRT method. Data Analyzed by SPSS software level of significance was below 0.05. Results : The range of patient’s age was 17 to 59 years. The mean of EDSS scores of men and respecting women was 2.69 micrometer and 2.86 micrometer that show no significant difference (P=0.63). Spearman Correlation showed that there is no statistically significant correlation between EDSS and mean RNFL thickness in both left and right eyes (P=0.081 for right and P=0.052 for left). Also there was no statistically significant correlation between EDSS and mean RNFL thickness of both eyes in patients with or without optic neuritis (P=0.66, 0.28). Mean RNFL thickness of both eyes showed no significant difference in patients with and without optic neuritis (0.209). Conclusion : This study pointed out that no decrease was detected in RNFL thickness by increasing EDSS scores using HRT method. There are evidences that both HRT and Optical Coherence Tomography (OCT) methods can show decreasing of RNFL but OCT appears to be more sensitive.
http://rjms.iums.ac.ir/article-1-1831-en.pdf
MS
EDSS
Retinal Nerve Fiber Layer
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-09
18
87
44
52
article
Results of radiofrequency tonsillotomy in adults with recurrent tonsillitis
Shademan Nemati
1
Abdolrahim Kousha
2
Rahmatollah Banan
3
Mir Mohammad Jalali
4
Hooshang Gerami
5
Ehsan Kazem Nejad
6
Nasim Kousha
7
Fataneh Bakhshi
8
Backgrounds : Tonsil reduction by use of Radiofrequency waves is one of the newest therapeutic modalities, especially for obstructive large tonsils. The aim of this study was comparing short term and long term results of radiofrequency tonsillotomy and traditional cold dissection tonsillectomy in adult patients with recurrent tonsillitis. Methods : a prospective randomized clinical trial on 72 adults with recurrent tonsillitis was performed in a tertiary referral university hospital. Traditional tonsillectomy in 34 cases and radiofrequency tonsillectomy (RF) by use of RFITT (Radiofrequency Induced Thermotherapy) probes in 38 cases were performed under general anesthesia. Time of surgery, amount of intraoperative bleeding, recovery time, post-surgical pain, dysphagia, weight loss, and time of return to normal diet and activity were measured. All the patients were followed for 24 months for recurrence of tonsillitis episodes. Statistical analysis was performed by use of SPSS version 16 software and X2 and Mann-Whitney U tests. Results : Mean time of surgery(16.89 vs. 46.07 minutes) and recovery(14.32 min vs. 17.11 min), and amount of intraoperative bleeding(15-20 cc vs. 250- 300cc) were significantly less in the RF group compared to traditional tonsillectomy group (P<0.005). There was no difference among two groups in the recurrence of tonsillitis episodes after 24 months. Conclusion : Tonsillotomy with RF is a simple, rapid, and effective method in adult patients with recurrent tonsillitis.
http://rjms.iums.ac.ir/article-1-1832-en.pdf
Radiofrequency tonsillotomy
traditional cold dissection tonsillectomy
Adult
Recurrent tonsillitis