per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-08
18
86
1
11
article
The Influences of long-term resistance training on Adiponectin and lipid profiles levels in obese men
Sirvan Atashak
1
Afshar Jafari
2
Mohammad Ali Azarbayjani
3
Background: The prevalence of obesity and its complications is rapidly increasing worldwide. Hence, the objective of this study was to determine the effects of 10 week progressive resistance training on serum levels of adiponectin and lipid profiles in obese men. Methods: In semi-experimental study, Sixteen obese men (Body Mass Index≥ 30, 18-32 years)) were selected between voluntary subjects and located randomize in to two resistance training (n=8) and control (n=8) groups. The experimental subjects received resistance training program. Progressive resistance training was performed three times a week on alternate days for 10 weeks and included 8 exercises. At baseline and after 10 weeks, Blood samples were taken in 12-14 hours fasting state from all subjects and investigated blood lipid profiles and adiponectin pre-post protocol. The paired and unpaired t-test in <0.05 significantly level were used in the statistical analysis. Results : Compared to pre-training, after 10 weeks progressive resistance training, the serum adiponectin levels significantly increased (P<0.05) and total cholesterol levels significantly decreased (P0.05). Conclusion : According to this study, resistance training because of anti-inflammatory and hypolipidaemic effects has been an effective therapeutic devise to favorable changes in lipid profiles and adiponectin levels in obese individuals.
http://rjms.iums.ac.ir/article-1-1657-en.pdf
Resistance training
Adiponectin
lipid profiles
obese men.
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-08
18
86
12
21
article
Effect of dimenhydrinate on benign paroxysmal positional vertigo
Poopak Izadi
1
Mohammad Ebrahim Yarmohammadi
2
Siamak Afshinmajd
3
Babak Izadi
4
Ali Davati
5
Hasan Ghasemi
6
Jaleh Iranmehr
7
Background: Benign Paroxysmal Positional Vertigo (BPPV) is the most common cause of peripheral vertigo in adults. Reason of this type of vertigo is movement of otoliths in semicircular canals (especially posterior). Main treatments for BPPV are antivertiginous drugs and maneuvertherapy. The purpose of this study is to determine the efficacy of Dimenhydrinate after maneuvertherapy of Epley on duration, number of vertigo attacks and duration of dizziness after each vertigo attack in patients with Posterior canal BPPV. Methods: one hundred forty eight patients with posterior Canal BPPV were evaluated in a randomized clinical trial in 2008 _2009.Maneuvertherapy of Epley were done for all patients. They were divided into two groups: Dimenhydrinate group (75) and Placebo group (73) and drug prescribed for 2 weeks. Patients were followed up after treatment for duration of vertigo (days), number of vertigo attacks and duration of dizziness after each vertigo attack (minute). Data were analyzed with statistical software SPSS 11/5 and comparison of means were done with T test and relationship between qualitative variables with X2 square. Results: Mean duration of recovery from vertigo attacks were 3/2±2/9 days in Dimenhydrinate and 3/8± 3/3 in Placebo groups, mean number of vertigo attacks after treatment were 2±0/7 in Dimenhydrinate and 2/2 ±1 in placebo groups and Mean duration of dizziness after each vertigo attack was 32/75± 2/07 minutes in Dimenhydrinate and 39 ± 3/55 minutes in placebo groups with no statistically difference (P<0/05). Conclusion: Epley maneuvertherapy is an effective treatment for Posterior canal BPPV and adding Dimenhydrinate does not increase its effectiveness.
http://rjms.iums.ac.ir/article-1-1658-en.pdf
Benign Paroxysmal Positional Vertigo (BPPV)
maneuvertherapy of Epley
Dimenhydrinate
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-08
18
86
22
30
article
Perinatal complications in substance using in pregnancy
Soraya Saleh Gargari
1
Masumeh Fallahian
2
Ladan Haghighi
3
Maryam Hosseinnezhad Yazdi
4
Elahe Dashti
5
Behrokh Sahebdel Nobari
6
Background: Substance abuse is a major public health issue in all over the world. The types and ingredients of drugs used in our country are different from other countries. The study was conducted to determine relationship between substance abuse during pregnancy, and perinatal complications in Iran. Methods: A retrospective cohort study was carried out over a 6 years period on all the substance user pregnant women (519 cases) and 519 non users attending 4 major educational university hospitals labor ward. All the substance user pregnant mothers abusing heroin, opium, crack, cannabis, crystal, methadone, and polydrug were included and compared to non-exposed ones. Results: Our study demonstrated a 0.5% prevalence of substance abuse in pregnant women. Opium (62.6%) was the most prevalent substance followed by crack (20.3%). Pre-term birth was higher in all substance user groups, the most in crack group (45.8%) with relative risk of 2.55. Neonatal abstinence syndrome developed in 38.7% of infants born of addicted mothers (40.4% crack, 38.6% opiates, 35.3% crystal and 45.5% poly drug use). Neonatal birth weight of infants of mothers using crack, opium and polydrug were significantly lower to non -users (P<0.05). Neonatal Intensive Care Unit (NICU) admission in substance using mothers was significantly higher than non-users (P < 0.001). Neonatal death was 10.1% in crack group (RR=3.48) and 5.8% in opium user group (RR=2.79) with significant difference with non-users (P<0.05). Conclusion: The frequent types of substances used during pregnancy in our country are different from others (opium was the most prevalent substance). Subsequently the frequencies of the complications during pregnancy are different. Substance abuse during pregnancy has increased risk of pre-term birth, Small for Gestational Age, NICU admission and neonatal death .
http://rjms.iums.ac.ir/article-1-1659-en.pdf
Perinatal complication
Substance use
pregnant mothers.
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-08
18
86
31
38
article
Study of relation between testosterone level with type 2 diabetes
Seyed Hossein Samedanifard
1
Soraya Doust Mohammadian
2
Azam Doust Mohammadian
3
Esmat Abdollah Pour
4
Saeedeh Ashrafi
5
Mitra Kazemi
6
Background : Diabetes mellitus is a common metabolic disease. Its association with low level of testosterone has already been shown in many studies. Considering the role of testosterone hormone in impotency, fatigue, and bone mass deficiency this study aimed to investigate the association between serum total testosterone, free testosterone index (FTI), and sex hormone-binding globulin (SHBG) with type 2 diabetic patients and other factors. Methods : A cross-sectional, analytic study was conducted on 38 non-diabetic and 36 diabetic men aged 40-60 years old with Body Mass Index (BMI) 18-40 (kg/m2). Fasting serum total testosterone, SHBG, FBS (Fasting Blood Sugar), HbA1C, and other hormone tests were measured at the department of endocrinology, Firouzgar Hospital. The association between serum testosterone level, SHBG, FTI with FBS, HbA1C, BMI, and other factors were separately measured. For quantitative parametric variables, independent sample T test was used. For non-parametric variables, Mann- Whitney test was used. Pearson’s correlation was performed to assess the correlation between quantitative variables. Results : The mean age of participants was 47.7±5.7 years. Serum total testosterone, FTI, and SHBG had no difference between case and control groups. No significant association was found between good glycemic control (HbA1C<7) and serum testosterone level. However, there was a negative correlation between BMI and age with testosterone level. Mean testosterone level of smokers was significantly lower than non-smokers (p=0.008).FSH (Fasting Stimulating Hormone) in diabetic group was significantly lower (p=0.04). Conclusion : Our study has shown that there was no relation between serum testosterone level with type 2 diabetes and glycemic control in men.
http://rjms.iums.ac.ir/article-1-1660-en.pdf
Glycemic control
type 2 diabetes
serum total testosterone
free testosterone index (FTI)
sex hormone-binding globulin (SHBG).
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-08
18
86
39
48
article
Association of TNF-α promoter G-308A Polymorphism and Body Mass Index and other obesity effective factors in Tehran Lipid and Glucose Study
Kobra Sharifi
1
Fatemeh Rostami
2
Bita Faam
3
Marayam Sadat Daneshpour
4
Fereydoon Azizi
5
Mehdi Hedayati
6
Background: obesity cause a lot of disease such as cardiovascular, type 2 diabetes, obstructive sleep apnea, some types of cancers and osteoarthritis. Reports show polymorphism at position -308 in the promoter region of TNF- α increase transcription of the gene in adipocytes. We, therefore, examined the relationship between this variant and BMI as an obesity criterion and other obesity affective factors in an Iranian population. Methods : 244 Subjects were randomly selected from the Tehran lipid and Glucose study which is a Cross Sectional Study and they were classified in two age groups under 18 and above 18. We measured FBS, HDL-C, LDL-C, triglyceride, cholesterol levels, CRP, IL-6, IL-10, Adiponectin, and HOMA for all individuals. Factors including Body mass index and blood pressure were measured too .A 107bp segment of the mentioned gene with PCR (Polymerase Chain Reaction) was amplified and the polymorphism with RFLP (Restriction Fragment Length Polymorphism) revealed. Undistributed Data were analyzed by kruskal-Wallis test and distributed Data were analyzed by ANOVA. We used one-way ANOVA test followed by post hoc multiple comparison (Tukey) to compare laboratory findings of BMI groups . All data were analyzed using SPSS 16. Results: The allele frequency of TNF-α polymorphism was in the Hardy Weinberg equilibrium and the Genotype of all 244 subjects were GG(85.7 % ), GA(13.1 % ),AA(1.2 % ) and there was no relation between BMI and the frequency of this allele. In adolescent sbp ) systolic blood pressure) in girls at GA state was significantly more than GG and CRP in boys at AA state was significantly more than the two other state In adult cholesterol in men at AA was significantly more than the two other state and LDL-C in women in GG was more than the two other state . Conclusion: Data from this study shows no association between G - 308A TNF-a promoter polymorphism with increasing BMI, so probably it is not important risk factor for obesity in Iranian populations.
http://rjms.iums.ac.ir/article-1-1661-en.pdf
Obesity
Polymorphism
Tumor Necrosis Factor-alpha
Anthropometric factors
Interleukin.
per
Iran University of Medical Sciences
Razi Journal of Medical Sciences
2228-7043
2228-7051
2011-08
18
86
49
58
article
Study of prevalence of violence against nurses and related factors
Mashallah Aghilinejad
1
Marzieh Nojomi
2
Seyed Mohammad Seyed Mehdi
3
Background: The risk of violence is higher in some occupations, including nursing. Also, violence is becoming more prevalent in health care settings. The first step for reducing violence is recognition of its potential risk factors. The aim of present study was assessment of violence against nurses and related risk factors in Iran. Methods: In this descriptive-analytical and cross-sectional study Persian version of NEXT questionnaire was used. Sampling method was multistep sampling. Stratification was performed based on the hospital and then in each hospital questionnaires was given to nurses non-randomly. 1070 nurses working in 14 TUMS (Tehran University of medical sciences) hospitals were included in the study. Results: Psychological violence from patients and their relatives against nurses included in the study was 60.3%. There was no significant relationship between age, sex, professional position, work experience, patients numbers who worked with participants in a single shift and average weekly work hours and psychological violence from patients and their relatives (P<0.05), but participants ward, work schedule, and work disturbances, had a significant relationship with psychological violence from patients/relatives. Conclusion: Based on this study, violence against nurses is a common and important problem and further studies aimed to reduce that, with regard to risk factors achieved in this study, is essential.
http://rjms.iums.ac.ir/article-1-1662-en.pdf
Violence
nurses
violence against nurses.