TY - JOUR JF - RJMS JO - RJMS VL - 8 IS - 23 PY - 2001 Y1 - 2001/6/01 TI - DETERMINATION OF SERUM 25-HYDROXY VITAMIN D3 LEVELS IN EARLY POSTMENOPAUSAL IRANIAN WOMEN: RELATIONS TO BONE MINERAL DENSITY AND URINE HYDROXYPROLINE TT - تعیین عیار سرمی 25- هیدروکسی ویتامین 3D در زنان یائسه ایرانی و بررسی ارتباط آن با میزان تراکم استخوان و سطح هیدروکسی پرولین اوره N2 -  Vitamin D plays an important role in calcium and phosphorus metabolism as well as bone and teeth growth and maintenance. In the present study, the vitamin D status in postmenopausal Iranian women and its relationship with bone mineral density (BMD) and urine hydroxyproline (OHPr) were determined. The serum levels of 25-hydroxyvitamin D3 (25-OHD3), BMD and OHPr assessed in 85 selected, early postmenopausal women (49-67 yr) referred to the Bone Densitometry Center, Loghman-Hakim Hospital, Tehran. The relations among them were also evaluated. Both 25-OHD3 and OHPr levels were measured for the first time in Iran using HPLC ( High Performance Liquid Chromatography) and spectrophotometric methods, respectively. BMD measured with dual energy X-ray absorptiometry in lumbar spine and proximal femur regions.  25-OHD3 levels ranged between 3.8-64.0 ng/ml (mean ± SD, 17.3 ± 11.4ng/ml). Thirty-two subjects (38%) were vitamin D deficient ( SP - 18 EP - 23 AU - Rassouli, A. AU - Milanian, I. AU - Moslemi Zadeh, M. AD - KW - 1) Vitamin D 2) Bone Mineral Density(BMD) 3) Postmenopausal 4) Osteoporosis 5) Hydroxyproline UR - http://rjms.iums.ac.ir/article-1-311-en.html ER -