TY - JOUR T1 - Effect of endurance training and omega-3 supplementation in brain-derived neurotrophic factor (BDNF) in male adult rat hippocampus TT - ﺗﺃثیر تمرین استقامتی و مصرف مکمل امگا-۳ بر عامل نوروتروفیک مشتق از مغز (BDNF) در هیپوکمپ موش‌های صحرایی نر بالغ JF - RJMS JO - RJMS VL - 20 IS - 111 UR - http://rjms.iums.ac.ir/article-1-2718-en.html Y1 - 2013 SP - 50 EP - 57 KW - Brain-derived neurotrophic factor (BDNF) KW - Omega-3 KW - Hippocampus KW - Physical endurance. N2 -  Background: This study was to examine the effects of endurance training and omega-3 supplementation in brain-derived neurotrophic factor (BDNF) in the male adult rat hippocampus.  Methods: Twenty eight Wistar rats were divided into four equal groups: control, exercise, diet, and exercise with diet Animals in the exercise group received 8 weeks of endurance training and animals in the diet group were treated with 100/mg/kg/day of omega-3 supplementation via oral gavage for 8weeks. The exercise with diet group received a combination of exercise and also supplementation. Hippocampal BDNF protein was assessed using commercial ELISA methods andthe data were analyzed by one-way ANOVA (p M3 ER -