TY - JOUR JF - RJMS JO - RJMS VL - 19 IS - 99 PY - 2012 Y1 - 2012/9/01 TI - Application of recurrent events model in determining the risk factors of recurrence of Schizophrenia TT - کاربرد مدل پیشامدهای بازگشتی در تعیین عوامل خطر بازگشت بیماری اسکیزوفرنیا N2 -   Background : Identifying the risk factors of recurrence of a disease is important both for physicians and patients. Analyzing the first recurrence may lead to an inaccurate evaluation of risk factors as it may not reflect the history of disease completely and may result in the loss of some valuable information. This study was aimed to analyze the time up to the recurrent relapses of schizophrenia as well as determining the risk factors that lead to the recurrence of the disease.   Methods: In this study 159 registered schizophrenia patients at Razi hospital were selected from a longitudinal study. The effect of age, sex, marriage, start of disease, and history of head trauma variables on recurrence of disease was assessed by a frailty model. Data analysis was made on by R 2.14.1.   Results: Mean of patients’ age was 21.5±6.6 year. Based on the Gamma frailty model, sex of patients (p=0.045) and history of head trauma (p=0.028) had significant effect on the hazard of recurrent relapses of Schizophrenia. In addition, the correlation of first, second and third times of recurrence was significant (p SP - 7 EP - 11 AU - Rahgozar, Mehdi AU - Cheraghi, Leila AU - Bakhshi, Enayatollah AU - Karimloo, Masoud AU - Fadaei, Farbod AU - Biglarian, Akbar AD - University of Social Welfare and Rehabilitation Sciences KW - Recurrent events KW - Frailty model KW - Relapses of disease KW - Schizophrenia UR - http://rjms.iums.ac.ir/article-1-2197-en.html ER -