TY - JOUR JF - RJMS JO - RJMS VL - 19 IS - 96 PY - 2012 Y1 - 2012/6/01 TI - The effects of salvia officinalis extract on serum level of creatine kinase and alkaline phosphatase in male rats TT - بررسی اثر عصاره گیاه مریم گلی بر سطح سرمی آنزیم های آلکالین فسفاتاز و کراتین کیناز در موش های صحرایی نر N2 -   Background : Studies show that there is association between Salvia officinalis extract administration and liver and heart functions. The main aim of this study was to determine the effects of Salvia officinalis extract on serum level of creatine kinase and alkaline phosphatase in male rats.   Methods : In this laboratory experimental study, m ale wistar rats were randomly divided into control, normal saline receiving and Salvia officinalis extract (100, 150 or 200 mg/kg/day) receiving animals of 5 in each group. After a period of 6 weeks, blood samples were collected using cardiac puncture method. Following serum collection, serum creatine kinase and alkaline phosphatase levels were measured by spectrophotometry method. Data were statistically analyzed and compared between groups using ANOVA.   Results : The results indicated that serum creatine kinase level was significantly decreased in rats receiving Salvia officinalis extract (100 mg/kg/day) compared with control animals (p SP - 20 EP - 25 AU - Ahmadi, Rahim AU - Abdollahy, Elahe AD - Tehran University of Medical Sciences KW - Salvia officinalis KW - Creatine kinase KW - Alkaline phosphatase KW - Rat. UR - http://rjms.iums.ac.ir/article-1-2132-en.html ER -