Volume 13, Number 53 (1-2007)                   RJMS 2007, 13(53): 169-175 | Back to browse issues page


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Mohebbi A, Emami A. A Case Report of Nasopharyngeal Neuroendocrine Carcinoma . RJMS. 2007; 13 (53) :169-175
URL: http://rjms.iums.ac.ir/article-1-662-en.html

Abstract:   (5045 Views)

    Introduction: Neuroendocrine carcinoma is one of the neoplasms of neuroendocrine system which involves organs sparing of APUD cells. The most common sites of this carcinoma are gastrointestinal and pulmonary system. From a histologic standpoint, these tumors are reactive to silver stains and specific markers like NSE(Neuron Specific Enolase), synaptophysin, and chromogranin A. Case Report: A 74-year-old woman with a complaint of 6-month nasal stuffiness, epistaxis, anosmia, and hearing loss was referred to the hospital. In her nasal examination, a vascular polypoid mass in nasopharynx was noticed. CT-scan showed a homogeneous, isodense mass in nasopharynx without bony erosion. Conclusion: After confirming the diagnosis of carcinoid tumor using specific markers and special stains, there are some factors to predict its malignancy. Systemic chemotherapy(esp. cisplatin & etuposide) is effective to treat malignant neuroendocrine tumors especially aggressive variants. Radiotherapy has palliative effect.

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Type of Study: case report | Subject: ENT

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