Razi Journal of Medical Sciences

Abstract

Background: Urinary tract infection is the most prevalent childhood infection and because of its complication requires antibiotic therapy. The aim of this study was frequency determination and antibiotic resistance pattern of UTI pathogens of children under 15 years old in Kermanshah.

Methods: This cross-sectional study was carried out on 121 positive urine cultures of children in 2015. After microorganism determination, antibiotic susceptibility test was done with disc diffusion method.

Results: Of  total 121 sample %69.4 were girls, %30.6 were boys and most of cases were girls under 2 years old. The most prevalent pathogens were E.coli (%71.1), Enterobacter (%14.9) and other pathogens (%14).Without considering the pathogen most antibiotic resistance were seen in ampicillin %90.8  coterimoxazol (%70.2) cephalexin (%67.7) and the most susceptibility were seen in ciprofloxacin (%82.7) and nitrofurantoin(%76.9) respectively.

Conclusion: In this study, ciprofloxacin and nitrofurantoin were the most effective antibiotics, which make these antibiotics valuable in UTI treatment. In addition, the increasing rate of cephalosporin resistance could be due to inappropriate consumption of these drugs. As a result, accurate attention to appropriate prescription of antibiotics, identifying the UTI pathogen and periodical epidemiological studies for identifying the resistance pattern seems necessary.