Volume 22, Issue 130 (4-2015)                   RJMS 2015, 22(130): 21-28 | Back to browse issues page

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Survival analysis of colorectal cancer patients and its prognostic factors using cox regression. RJMS. 2015; 22 (130) :21-28
URL: http://rjms.iums.ac.ir/article-1-3720-en.html
Abstract:   (1673 Views)

Background: Colorectal cancer is the third current cancer in the world and the forth cause of death in cancers. Certain factors such as environmental, genetic and life style are related with this cancer. The objective of this study is to find the survival of Iranian patients with colorectal cancer and also to find its prognostic factors.


Methods: In this survival study, the data was collected from colorectal cancer patients who had referred to Fayyazbakhsh Hospital in Tehran from 2007 to 2009, using their hospital records. The final situation of the patients was recorded in 2012. For survival analysis of the patients, Kaplan-Meier method was used. The prognostic factors were calculated using Cox Regression.


Results: The median of survival for the patients was (38.8±0.35) month. The one and 5 years survival rates were 79.2% and 39.6%, respectively. The effect of metastasis in prognostic time, age, having surgery and grading were significant using multivariate analysis. The high age, having surgery and the increase of virulent degree were the causes of patients’ survival reduction using Cox regression.


Conclusion: The five year survival rate is less than western countries. Since there are many young colorectal cancer patients in the country, it is possible to increase their life using screening tests and early diagnostic programs.



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Type of Study: Research | Subject: Biostatistics

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