Volume 23, Number 147 (9-2016)                   RJMS 2016, 23(147): 11-17 | Back to browse issues page


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اraeeszadeh M, ahmadi E, shafiee M. Identification of the antibiotic resistance patterns in bacteria isolated from urinary tract infections in patients admitted to Shahid Ghazi Hospital-Sanandaj in the first 6 months of 1393. RJMS. 2016; 23 (147) :11-17
URL: http://rjms.iums.ac.ir/article-1-3404-en.html

Abstract:   (1788 Views)

  Abstract

  As an inappropriate antibiotic administration, the emergence of drug resistance in pathogens associated with clinical and subclinical urinary duct infections is of great concern worldwide. The present cross-sectional study was conducted on 114 patients affected with urinary duct infections and admitted to Shahid Ghazi Hospital in the first half of 1393, on the aim of the bacteriological evaluation of urine samples and identification of antimicrobial resistance profile of the isolated bacteria. The youngest patient was 9 and the oldest one was 85 years old, and 96% were women and 4% were men. The relative frequency of bacteria isolated from the urine samples in bacterial culture were 74% Escherichia coli, 20% Staphylococcus spp., 3% Streptococcus spp., 2% Klebsiella spp., and 1% Pseudomonas spp. The antibiotic susceptibility profile was investigated by antibiogram test in accordance with NCCL protocol. The standard used antibiotic discs contained sulfamethoxazole, ceftizoxime, tetracycline, amikacin, cephalexin, nalidixic acid, gentamicin, nitrofurantoin, cefotaxime, ciprofloxacin, ampicillin, vancomycin, co-trimoxazole and norfloxacine. The most and the least susceptibility in Escherichia coli were for nitrofurantoin and sulfamethoxazole, respectively. Staphylococcus and Streptococcus isolates had the most resistance to ampicillin and sulfamethoxazole and the most susceptibility to nitrofurantoin and gentamicin. Klebsiella and Pseudomonas had the most antibiotic resistance for tetracycline and co-trimoxazole and the most susceptibility to gentamicin and amikacin, respectively.

  Based on the importance of antibiotic resistance emerging and the alteration in antimicrobial resistance pattern of bacteria, antibiogram tests are essential for treatment of urinary tract infections.

  

  Keywords : urinary tract infections (UTI), antibiotic resistance patterns, antibiogram testing

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Type of Study: Research | Subject: Pharmacology

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