Volume 4, Issue 1 And 2 (9-1997)                   RJMS 1997, 4(1 And 2): 11-16 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jadali F, Vahidi S. ALIGNANT PERIPHERAL NERVE SHEATH TUMOR (A CASE REPORT). RJMS. 1997; 4 (1 and 2) :11-16
URL: http://rjms.iums.ac.ir/article-1-1807-en.html
Abstract:   (4911 Views)

Malignant peripheral nerve sheath tumor (MPNST) is an aggressive neoplasm of neural origin. It is a rare neoplasm of childhood, accounting for less than 5% of all cases.

In 1994 a 29 months old boy was admitted to the Mofid Hospital with complaints of fever, dyspnea and respiratory distress.

After performing all the necessary clinical and labratory tests a large mass in the upper posterior mediastinum was detected. The tumor was resected.

Pathological examination of the tumor showed a malignant neoplastic tissue composed of round atypical cells with hyperchromatic and vesicular nuclei and eosinophilic cytoplasm similar to rhabdomyoblasts pseudorossettes and areas of necrosis and hemorrhage were evident.

On immunohistochemical study, the tumor cells were positive for S100 protein, NSE, vim entin, keratin and EMA.

Diagnosis of MPNST was confirmed by clinical manifestation, pathologic findings and immunohistochemical studies.

Full-Text [PDF 1092 kb]   (1034 Downloads)    
Type of Study: case report | Subject: immunopatology

Add your comments about this article : Your username or Email:
Write the security code in the box

© 2018 All Rights Reserved | Razi Journal of Medical Sciences

Designed & Developed by : Yektaweb