Volume 10, Number 33 (6-2003)                   RJMS 2003, 10(33): 9-15 | Back to browse issues page


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Barati M, Eshaghi M, Noori N. EVALUATION OF CORRELATION BETWEEN ESR AND CRP WITH OSTEOMYLITIS IN DIABETIC FOOT. RJMS. 2003; 10 (33) :9-15
URL: http://rjms.iums.ac.ir/article-1-132-en.html

Abstract:   (8806 Views)
Infection is a common complication of diabetic foot that needs hospital admission and surgical intervention.Diabetic foot occurs in one of each ten diabetic patients. Diabetic foot complications are osteomyelitis, arthritis and abscess formation. Radiography, isotope scans, MRI and CT-scan are the procedures that help diagnosis of these complications but these are not always cost effective or available. If ESR and CRP level could help us to determine depth and width of diabetic foot ulcer and the possibility of presence of osteomyelitis, we can cost saving and begin appropriate therapy very soon. A retrospective chart review of 35 diabetic patients admitted to the Rassol Akram Hospital with diagnosis of osteomyelitis or cellulites of the foot during a 2-year periods (1999-2000) was performed. Depth and width of ulcer, presence or absence of osteomyelitis, ESR and CRP level are compared in this group. A retrospective review of 35 diabetic patients that admitted to this hospital only for control of blood glucose also was performed as control group. In this survey ESR and CRP level in diabetic foot group was higher than control group(P.value=0.00), and in diabetic foot with osteomyelitis was higher than diabetic foot without osteomyelitis(P.value=0.001 for ESR and P.value=0.00 for CRP). CRP level in large ulcers were higher than small ulcers(P.value=0.001). ESR and CRP level in patients with long duration of admission were higher than patients with short duration (P.value=0.00 for ESR and P.value=0.001 for CRP). We concluded that higher ESR and CRP level is seen in diabetic foot with osteomyelitis and higher CRP level is indicated of the presence of large ulcer and if patient with diabetic foot has a high ESR and CRP level, need a long period of treatment. We concluded that in diabetic foot only when ESR and CRP level is high investigation for presence of osteomyelitis could be necessary.
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Type of Study: Research | Subject: Infectious Disease

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